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Short answer
Add the person to Whitelist Contacts in Account Settings, on the Automation tab, or click Exclude from automation on their contact in Contacts. Whitelisted people get no automations at all: no DMs, no public replies, no flows and no follow-ups.
“Whitelist” here means the opposite of what it sounds like: people on this list are skipped by every automation.
Option A: by username, in Settings
Option B: from Contacts
Option B adds them to the same Whitelist Contacts list, using their account number instead of their username.
Tap your profile photo, then Settings → Automation. Under Whitelist Contacts, type the username, tap Add, then tap Save Changes.
Nothing from your automations. They can still comment and message you, and you can reply to them yourself in Instagram or Facebook.
Open Account Settings → Automation → Whitelist Contacts, click the × on the entry, then click Save. Entries added from Contacts show as a number, for example “@1784…”.
No. The settings text mentions Flow, Lead-gen and AI, but a whitelisted person gets no automation of any kind, including comment replies and Send Link DMs.
Open Account Settings, go to the Automation tab, find Whitelist Contacts and click the × on that entry. Then click Save.
Use Human takeover instead. It silences only AI Reply steps for that person, and your other automations keep running.