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Short answer
In the comment automation editor, turn on the Welcome Message, then under Send a DM! choose DM Sequence. Add up to 10 messages with + Add Message and set a delay in minutes for message 2 onward. After the person taps the welcome button, the messages arrive in order. DM Sequence is on Legend Pro and above.
In the post editor (Send Link or Images → Edit Automation), open Send a DM! and choose DM Sequence (“Create up to 10 messages in your sequence”). Each message can be text, a button card, an image, audio or a PDF. From message 2 on, set “⏱️ Send after [ ] minutes (0 - 1440)”. Add more with + Add Message, then tap Publish.
Switch back to Single Message, or switch off the automation. See turn off, edit or delete an automation.
Instagram allows one private reply to a comment. When the person taps the welcome button, a normal chat opens and the rest of your messages can follow. That is why a second message needs the Welcome Message or the follow gate on.
No. A DM Sequence sends on a timer. To wait for an answer or react to it, use Flow Automation (Trendsetter and above).
You set it in minutes. Instagram only lets you message someone within 24 hours of their last message or button tap, so keep the whole sequence inside 24 hours.